The Top Ten Household Toxins Affecting Pets
- Dr. Zeke Zekoff
- Apr 23
- 2 min read

Pet Poison Helpline has compiled a list of the most common household toxins that lead to emergency calls from pet owners each year. These insights aim to help pet owners better understand and prevent poisoning risks for their furry companions.
Top Ten Toxins for Dogs
Dogs are naturally curious, which can sometimes lead them to ingest harmful substances. The most frequent offenders include:
Chocolate – The darker the chocolate, the more toxic it is. Bakers and dark chocolate are particularly dangerous, potentially causing vomiting, tremors, and cardiac issues.
Xylitol – Found in sugar-free gum, candy, and medications, this sweetener can lead to rapid drops in blood sugar and liver failure in dogs.
NSAIDs (Ibuprofen, Naproxen, etc.) – Pain relievers like Advil and Aleve can cause stomach ulcers and kidney failure in dogs.
Over-the-counter cold and allergy medications – Medications containing acetaminophen or decongestants such as pseudoephedrine pose serious health risks.
Rodenticides – Mouse and rat poisons can lead to internal bleeding or neurological damage.
Grapes and Raisins – Even in small amounts, these foods can cause kidney failure.
Insect bait stations – While not highly toxic, ingestion of plastic casings may cause intestinal blockage.
Prescription ADD/ADHD medications – Amphetamines like Adderall and Vyvanse can trigger seizures, tremors, and heart problems.
Glucosamine joint supplements – Though usually harmless, overdoses can rarely lead to liver complications.
Silica gel packets and oxygen absorbers – Silica gel packs found in packaging are generally safe, but iron-containing oxygen absorbers from food packages can lead to iron poisoning.
Top Ten Toxins for Cats
Cats are uniquely sensitive to certain household items, including:
Lilies – Flowers such as Easter, Tiger, and Asiatic lilies are highly toxic and can cause kidney failure.
Household cleaners – While general-purpose cleaners are fairly safe, concentrated products can cause chemical burns.
Flea and tick products for dogs – Pyrethroids in certain treatments can be fatal to cats.
Antidepressants – Some antidepressants, such as Cymbalta and Effexor, can lead to severe neurological issues in cats.
NSAIDs (Ibuprofen, Naproxen, etc.) – Cats are particularly vulnerable to these drugs, with even veterinary-specific NSAIDs requiring caution.
Prescription ADD/ADHD medications – Similar to dogs, cats react poorly to amphetamines and may suffer tremors or seizures.
Over-the-counter cold and allergy medications – Acetaminophen can cause serious red blood cell damage and liver failure.
Houseplants with calcium oxalate crystals – Plants like peace lilies and pothos may cause oral irritation but rarely lead to severe symptoms.
Household insecticides – Though generally safe, cats should avoid exposure to sprays and powders until they have settled.
Glow sticks and glow jewelry – These playful items contain dibutyl phthalate, which can lead to mouth irritation and excessive drooling.
Emergency Response for Pet Poisoning
If a pet ingests a toxic substance, immediate action is necessary. Contact a veterinarian or Pet Poison Helpline at 1-800-213-6680 for guidance. The organization also offers a mobile app with a database of common pet toxins.
By spreading awareness and pet-proofing homes, owners can reduce the risk of poisoning and keep their pets safe.
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